Do the Results of Pregnancy Registries Contradict One Another?
نویسندگان
چکیده
منابع مشابه
Antiepileptic drug pregnancy registries: do the latest findings concur?
Registry versus clinical trial The main goal of pregnancy registries includes the rapid identification of signals of increased teratogenic risk as quickly as possible, which is especially important for newly available anti epileptic drugs (AEDs) [1–3]. When the association between an increased risk and an AED is found in a registry, the cause can be further explored in a case–control study or a...
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The risk of major malformations in the offspring of mothers with epilepsy receiving antiepileptic drugs is 4--8% compared to 2--4% in the general population. Risk factors include daily dose and polytherapy. Selected drugs have been found to be associated with a higher risk of specific malformations (congenital heart defects and cleft palate with phenytoin and barbiturates; neural tube defects w...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2006
ISSN: 1535-7597,1535-7511
DOI: 10.1111/j.1535-7511.2006.00102.x